Institut für Marine Biotechnologie e.V. (IMaB)
Marine microorganisms are a prolific resource of new technical enzymes and pharmacologically active agents or lead structures. Their special living conditions and functions in the ecosystem force them to produce a vast number of enzymes with unique activities and bioactive metabolites with new structures.
The main Topics of activities at the IMAB are:
Bioactive compounds
- Screening and characterisation of cyanobacteria and marine fungi producing substances with antibacterial, antifungal, antiviral, cytostatic, immunomodulatory or enzyme inhibitory properties
- Isolation, structure elucidation and analysis of bioactive compounds-cultivation of marine microorganisms
- Target analyses (Proteomics)
Cold-adapted enzymes
- Screening of psychrophilic microorganisms with cold-adapted enzymatic activities
- Cloning and expression of cold-adapted enzymes
Enzyme production processes
- Development of bacterial expression systems for the overproduction of thermolabile or insoluble enzymes
- Optimisation of bacterial fermentation processes
- Quality control of recombinant enzymes by proteomics
MIMAS
stands for Microbial Interactions in MArine Systems. The Objectives of the project are:
- Adaptation of state of the art molecular biological techniques for metatranscriptome and metaproteome analyses for the determination of complex marine microbial assemblages
- Evaluation of these techniques as future tools for the analysis of bacterial mediated ecosystem functions at two marine model habitats
- Development of software tools for the integration of diversity and metagenome data with gene expression data and biogeochemical parameter
Contact:
Institut für Marine Biotechnologie e.V.
Walther-Rathenau-Str. 49A
D-17489 Greifswald
Phone +49(0)3834 864212
Fax +49(0)3834 864238
E-Mail: info@marine-biotechnologie.de
www.marine-biotechnologie.de
